AOA2 | als4

Discovery Medicine: February 2015

Unwinding the Role of Senataxin in Neurodegeneration. Published: Discovery Medicine; ISSN: 1539-6509; Discov Med 19(103):127-136,...

Genes and Development: April 2014

A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to...

Identification of the ALS4 Gene Mutation: June 2004

DNA/RNA Helicase Gene Mutations in a Form of Juvenile Amyotrophic Lateral Sclerosis (ALS4). Published: American Journal of Human Genetics...

NIH Research: March 2014

Clinical and Molecular Aspects of Senataxin Mutations in Amyotrophic Lateral Sclerosis 4

Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in

Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Pro

Beyond DNA: March 2016

Discovery Medicine: February 2015

Genes and Development: April 2014

NIH Research: March 2014

PLOS: November 2013

Genes & Development: October 2013

Identification of the ALS4 Gene Mutation: June 2004

ALS4